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S 545On FloorFederalsenate

Combating Illicit Xylazine Act

Introduced February 12, 2025Last action April 15, 2026
View official bill

Legislative Progress

Introduced
Referred
Committee
Floor Vote
Passed Chamber
Passed Both
Enrolled
Signed

Plain English Summary

AI-generated

Combating Illicit Xylazine Act – Plain English Summary

This bill focuses on addressing the growing public safety threat posed by xylazine, a powerful sedative drug that is increasingly being mixed with illicit drugs like fentanyl on the street. Xylazine is a veterinary medication — meaning it is legally approved for use in animals, not humans — but it has been appearing more frequently in the illegal drug supply. The bill aims to control and restrict xylazine by placing it under federal drug scheduling laws, making its unauthorized possession and distribution illegal under the Controlled Substances Act.

By scheduling xylazine as a controlled substance, the bill would give law enforcement new legal tools to prosecute those who distribute it illegally. It would also create stricter oversight of how the drug is manufactured, distributed, and handled — similar to the controls already in place for other regulated substances. People who are caught illegally possessing or trafficking xylazine could face federal criminal penalties under this framework.

The bill primarily affects drug traffickers and others who distribute xylazine outside of legal channels, as well as veterinary and medical professionals who work with the drug and would need to comply with new regulations. It could also have indirect effects on communities dealing with the opioid and synthetic drug crisis, since xylazine mixed with fentanyl has been linked to particularly dangerous overdoses and severe skin wounds that are difficult to treat medically.

The bill was introduced in the Senate and has been reviewed by the Senate Judiciary Committee, which approved it with some modifications. It has not yet been passed into law.

This summary is AI-generated for informational purposes. Always refer to the official bill text for legal accuracy.

Latest Action

Placed on Senate Legislative Calendar under General Orders. Calendar No. 372.

April 15, 2026

Sponsor

S
Sen. Cortez Masto, Catherine [D-NV]DNV

Committees

the Judiciary

Legislative History

Committee on the Judiciary. Ordered to be reported with an amendment in the nature of a substitute favorably.

Mar 26, 2026

Read twice and referred to the Committee on the Judiciary.

Feb 12, 2025

Introduced in Senate

Feb 12, 2025